Hydroxy-PP-Me is a selective CBR1 inhibitor with an IC 50 of 759 nM. Hydroxy-PP-Me can inhibit serum starvation-induced apoptosis . Hydroxy-PP-Me can enhance the cytotoxic effects of Daunorubicin ( HY-13062A ) and As 2 O 3 on tumor cells. Hydroxy-PP-Me can be used in the research of cancer such as leukemia.
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