PI3K/HDAC-IN-3

Overview

PI3K/HDAC-IN-3 (36) is a PI3K and HDAC dual inhibitor, with IC 50 values of 0.23 nM and 172 nM for PI3Kα and HDAC1 , respectively. PI3K/HDAC-IN-3 (36) suppresses AKT phosphorylation and increased H3 acetylation in MV4-11 cells. PI3K/HDAC-IN-3 (36) exhibits significant and dose-dependent anticancer efficacy in a MV4-11 xenograft model.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > HDAC

Product Information

• Catalog No.: HY-157295
• CAS No.: 3006905-22-9
• Molecular Formula: C34H34F2N6O5S
• Molecular Weight: 676.73
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source