AK-HW-90

Overview

AK-HW-90 (compound 2B) is a potent pan Bcr-Abl inhibitor with significant inhibitory activity against Imatinib ( HY-15463 )-resistant mutants. AK-HW-90 inhibits the resistance mutant Bcr-Abl T315I with an IC 50 of 0.65 nM. AK-HW-90 has potential anticancer activity and can be used in the study of chronic myelogenous leukemia (CML).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Signaling Pathways > Bcr-Abl

Product Information

• Catalog No.: HY-157389
• CAS No.: 3072856-03-9
• Molecular Formula: C27H29N5O2S
• Molecular Weight: 487.62
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source