CCR4 antagonist 4

Overview

CCR4 antagonist 4 (compound 22) is a selective and potent antagonist of the CC chemokine receptor-4 ( CCR4 ) , with an IC 50 of 0.02 μM. CCR4 antagonist 4 also blocks MDC-mediated chemotaxis ( IC 50 : 0.007 μM) and Ca 2+ mobilization ( IC 50 : 0.003 μM). CCR4 antagonist 4 can be used for allergic inflammation research.

Application

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Product Information

• Catalog No.: HY-157453
• CAS No.: 668980-17-4
• Molecular Formula: C24H27Cl2N7O
• Molecular Weight: 500.42
• Purity: 98.92%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (5.00 mM); Clear solution
• Availability: In-stock

Source

Original product source