DSP-0390

Overview

DSP-0390 is an orally effective inhibitor of Emopamil-binding protein ( EBP ). DSP-0390 blocks the cholesterol de novo synthesis pathway in tumor cells by inhibiting EBP, and demonstrates significant anti-tumor activity in an orthotopic xenograft model of glioblastoma (GBM). DSP-0390 can be used for the study of recurrent high-grade gliomas.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > CNS Neoplasm | Products > Disease Areas > Glioma | Products > Disease Areas > Glioblastoma | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Emopamil Binding Protein

Product Information

• Catalog No.: HY-157828
• CAS No.: 2376765-57-8
• Molecular Formula: C23H30ClN3O2
• Molecular Weight: 415.96
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source