CYP1B1-IN-7

Overview

CYP1B1-IN-7 (compound 2a) is a selective inhibitor of CYP1B1 ( IC 50 : 75 nM). CYP1B1-IN-7 also reverses resistance ( IC 50 : 29 μM) and exhibits cytotoxicity in the CYP1B1-overexpressing MCF-7 cell line that is resistant to Docetaxel ( HY-B0011 ).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Cytochrome P450

Product Information

• Catalog No.: HY-157942
• CAS No.: 52601-58-8
• Molecular Formula: C19H13ClO
• Molecular Weight: 292.76
• Purity: 99.88%
• Storage: -20°C, protect from light * The compound is unstable in solutions, freshly prepared is recommended.
• Solubility: ≥ 1.67 mg/mL (5.70 mM); Clear solution
• Availability: In-stock

Source

Original product source