Nemorubicin (GMP)

Overview

Nemorubicin (Methoxymorpholinyl doxorubicin) GMP is a GMP-class Nemorubicin ( HY-15794 ). Nemorubicin is a Doxorubicin derivative with potent antitumor activity. Nemorubicin is highly cytotoxic to a variety of tumor cell lines presenting a multidrug-resistant phenotype. Nemorubicin not only intercalate into the duplex DNA, but also result in significant ligands for G-quadruplex DNA segments, stabilizing their structure. Nemorubicin requirs an intact nucleotide excision repair (NER) system to exert its activity.

Application

Products | Products > GMP Small Molecules | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > G-quadruplex

Product Information

• Catalog No.: HY-15794G
• CAS No.: 108852-90-0
• Molecular Formula: C32H37NO13
• Molecular Weight: 643.64
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source