BBO-8520

Overview

BBO-8520 is a direct small molecule covalent inhibitor targeting KRAS G12C with high oral availability. BBO-8520 has the characteristics of KRAS G12C (OFF) inhibitor and the function of blocking KRAS G12C (ON) signal. BBO-8520 inhibits cell proliferation by inhibiting KRAS G12C (ON) by binding GTP protein. BBO-8520 can block RAS-RAF1 interaction and return KRAS G12C to the inactive (OFF) state. BBO-8520 can be used for the research of cancer .

Application

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Product Information

• Catalog No.: HY-158107
• CAS No.: 2893809-51-1
• Molecular Formula: C35H33F6N7O2S
• Molecular Weight: 729.74
• Purity: 99.36%
• Storage: 4°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (3.43 mM); Clear solution
• Availability: In-stock

Source

Original product source