(4R)-BBO-8520

Overview

(4R)-BBO-8520 (Compound 314), an isomer of BBO-8520 ( HY-158107 ), is a selective KRAS G12C inhibitor. BBO-8520 has the characteristics of KRAS G12C (OFF) inhibitor and the function of blocking KRAS G12C (ON) signal. BBO-8520 inhibits cell proliferation by inhibiting KRAS G12C (ON) by binding GTP protein. BBO-8520 can block RAS-RAF1 interaction and return KRAS G12C to the inactive (OFF) state. (4R)-BBO-8520 can be used for the research of cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Others | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Drug Isomer | Products > Signaling Pathways > Ras

Product Information

• Catalog No.: HY-158107A
• CAS No.: 2893809-52-2
• Molecular Formula: C35H33F6N7O2S
• Molecular Weight: 729.74
• Purity: 99.98%
• Storage: 4°C, protect from light, stored under nitrogen * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)
• Solubility: ≥ 2.5 mg/mL (3.43 mM); Clear solution
• Availability: In-stock

Source

Original product source