TK-642 is a highly active, selective, orally activity SHP2 inhibitor based on pyrazole and pyrazine ( IC 50 =2.7 nmol/L). TK-642 can effectively inhibit the proliferation of esophageal carcinoma cells and induce cell apoptosis . TK-642 can be used in the study of esophageal cancer .
Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > SHP2
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