DMOG

Overview

DMOG (Dimethyloxallyl Glycine) is a cell permeable and competitive inhibitor of HIF-PH , which results in HIF-1α stabilisation and accmulation in vitro and in vivo. DMOG is an α-ketoglutarate analogue and inhibits α-KG-dependent hydroxylases. DMOG acts as a pro-angiogenic agent and plays a protective role in experimental model of colitis and diarrhoea via HIF-1 related signal. DMOG induces cell autophagy .

Application

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Product Information

• Catalog No.: HY-15893
• CAS No.: 89464-63-1
• Molecular Formula: C6H9NO5
• Molecular Weight: 175.14
• Purity: 99.93%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months
• Solubility: 150 mg/mL (856.46 mM); Clear solution; Need ultrasonic
• Availability: In-stock

Source

Original product source