MMs02943764

Overview

MMs02943764 is a 1,2,4-triazole derivative with anticancer activity. MMs02943764 has significant antiproliferative effects on multiple cancer cell lines. PAC, a structural analog of MMs02943764, has significant cytotoxicity against the leukemia cell line K562 ( IC 50 =35.264 μM), reduces the degradation of p53 by inhibiting Mdm2 and Pirh2 , and induces K562 cell cycle arrest.

Application

Products | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MDM-2/p53

Product Information

• Catalog No.: HY-158968
• CAS No.: 708287-29-0
• Molecular Formula: C24H25BrF2N4O2S
• Molecular Weight: 551.45
• Purity: 98.0%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (4.53 mM); Clear solution
• Availability: In-stock

Source

Original product source