SDUY038 is a SHP2 allosteric inhibitor, with an IC 50 of 1.2 μM and K D of 0.29 μM, respectively. SDUY038 exhibits pan-antitumor activity (IC 50 = 7-24 μM) by suppressing pERK expression. SDUY038 exhibits t 1/2 of 3.95 h by oral administration.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > SHP2
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