CH5164840

Overview

CH5164840 (16) shows high binding affinity for N-terminal Hsp90a (K d = 0.52 nM) and strong anti-proliferative activity against human cancer cell lines (HCT116 IC 50 = 0.15 μM, NCI-N87 IC 50 = 0.066 μM). CH5164840 (16) is orally active (t 1/2 = 2.64 h) with potent antitumor efficacy.

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > HSP

Product Information

• Catalog No.: HY-15990
• CAS No.: 1052645-73-4
• Molecular Formula: C19H23N5O2S
• Molecular Weight: 385.48
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source