KRN7000 analog 3 (Compound 14),α-GalCer ( HY-102022 ) analogue, is a iNKT agonist. KRN7000 analog 3 induces higher levels of IL-2 cytokine secretion (49.2-62.6 ng/mL) than a-GalCer (44.1 ng/mL) in mNK1 .2 cells. KRN7000 analog 3 is promising for research of antitumor agents and vaccine adjuvants.
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