QI-18 is a fibroblast activation protein ( FAP ) inhibitor with the IC 50 of 0.50 nM, which is a 6.5-fold increase in potency over that of UAMC-1110 (HY-100684, IC 50 of 3.25 nM). QI-18 can be used to synthesize high tumor selectivity and high dose radiotracers for the diagnosis and study of tumors.
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