PTK7/β-catenin-IN-2

Overview

PTK7/β-catenin-IN-2 (compound 04967) is an inhibitor of PTK7 / β-catenin . It inhibits the binding of PTK7 to β-catenin (IC 50 : 5.6 μM), thereby inhibiting the signaling of the Wnt/β-catenin pathway. PTK7/β-catenin-IN-2 targets cell growth dependent on the Wnt signaling pathway and has anticancer properties. PTK7/β-catenin-IN-2 also showed inhibitory potency against p53 and MDM2 binding with an IC 50 of 157.1 μM.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Signaling Pathways > β-catenin | Products > Signaling Pathways > Wnt

Product Information

• Catalog No.: HY-160489
• CAS No.: 902434-29-1
• Molecular Formula: C30H34Cl2N6O
• Molecular Weight: 565.54
• Purity: 96.96%
• Storage: 4°C, protect from light * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
• Availability: In-stock

Source

Original product source