Silatecan

Overview

Silatecan (AR-67) is a blood-brain barrier-permeable derivative of Camptothecin ( HY-16560 ), DNA topoisomerase I inhibitor, an anticancer agent, and a radiosensitizer. Silatecan potently radiosensitizes wild-type p53 gliomas. Silatecan can be used in research related to glioma, leukemia, non-small cell lung cancer , colon cancer , ovarian cancer , renal cancer , prostate cancer , breast cancer , cervical cancer , gastric cancer , nasopharyngeal cancer , and uterine cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Others | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Topoisomerase | Products > Signaling Pathways > Drug Derivative | Products > Signaling Pathways > MDM-2/p53

Product Information

• Catalog No.: HY-16055
• CAS No.: 220913-32-6
• Molecular Formula: C26H30N2O5Si
• Molecular Weight: 478.61
• Purity: 96.62%
• Storage: -20°C, sealed storage, away from moisture and light * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
• Solubility: ≥ 2.5 mg/mL (5.22 mM); Clear solution
• Availability: In-stock

Source

Original product source