PLK1/BRD4-IN-3

Overview

PLK1/BRD4-IN-3 (Compound 21) is a selective dual inhibitor for bromodomain 4 ( BRD4 ) and polo-like kinase 1 ( PLK1 ). PLK1/BRD4-IN-3 inhibits BRD4-BD1, PLK1 and BRDT-BD1, with IC 50 s of 0.059, 0.127 and 0.245 μM, respectively.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Epigenetic Reader Domain | Products > Signaling Pathways > Polo-like Kinase (PLK)

Product Information

• Catalog No.: HY-160558
• CAS No.: 2251709-91-6
• Molecular Formula: C31H43N7O3
• Molecular Weight: 561.72
• Purity: 98.55%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 1.67 mg/mL (2.97 mM); Clear solution
• Availability: In-stock

Source

Original product source