Menin-MLL-IN-32

Overview

Menin-MLL-IN-32 (compound 51) is a Menin-MLL interaction inhibitor with an IC 50 of 0.042 nM in HTRF assay. Menin-MLL-IN-32 inhibits MEIS1 mRNA expression with an IC 50 of 11 nM. Menin-MLL-IN-32 shows anti-proliferative effects, with IC 50 values of 8 nM, 24 nM and 1900 nM for MOLM14 cells, OCI-AML3 cells and KO-52 cells, respectively. Menin-MLL-IN-32 can be used for the study of leukemia.

Application

Products | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Epigenetic Reader Domain

Product Information

• Catalog No.: HY-160733
• CAS No.: 2879330-24-0
• Molecular Formula: C32H42FN5O2
• Molecular Weight: 547.71
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source