NCGC1481

Overview

NCGC1481 is an inhibitor of FLT3 , IRAK1 , and IRAK4 , with IC 50 values of <0.5 nM, 22.6 nM, and 0.8 nM, respectively. NCGC1481 can effectively overcome the adaptive resistance of leukemia cells to FLT3 inhibitors and has antileukemic activity.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > FLT3 | Products > Signaling Pathways > IRAK

Product Information

• Catalog No.: HY-160787
• CAS No.: 2193085-94-6
• Molecular Formula: C21H23N7O
• Molecular Weight: 389.45
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Solubility: ≥ 5 mg/mL (12.84 mM); Clear solution

Source

Original product source