DB07006

Overview

DB07006 (compound 18) is a potent, ATP-cpmpetitive dual inhibitor of Wee1 ( IC 50 = 0.030 μM) and Chk1 checkpoint kinases ( IC 50 = 0.018 μM). DB07006 demonstrates effective abrogation of the G2/M checkpoint in combination with DNA-damaging agents in cellular models. DB07006 can be used for cancer research.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Wee1 | Products > Signaling Pathways > Checkpoint Kinase (Chk)

Product Information

• Catalog No.: HY-160948
• CAS No.: 622855-60-1
• Molecular Formula: C24H20N2O5
• Molecular Weight: 416.43
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source