TP0628103 TFA

Overview

TP0628103 TFA is a potent and highly selective MMP-7 inhibitor with an IC 50 of 0.17 nM. TP0628103 TFA undergoes structural optimization via molecular isoelectric point shifting, which reduces organic anion transporter ( OAT )-mediated clearance, while maintaining potent MMP-7 inhibitory activity and enhancing MMP subtype selectivity. TP0628103 TFA is applicable for research on the regulatory mechanisms of MMP-7-related matrix metalloproteinases .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MMP

Product Information

• Catalog No.: HY-161169A
• CAS No.: 2865106-78-9
• Molecular Formula: C53H68ClF6N11O13S
• Molecular Weight: 1248.68
• Purity: 99.90%
• Storage: Sealed storage, away from moisture. Powder -80°C, 2 years , -20°C, 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (2.00 mM); Clear solution
• Availability: In-stock

Source

Original product source