Canfosfamide

Overview

Canfosfamide (TLK-286, TER286) is a glutathione analogue prodrug that is activated by glutathione S-transferase P1-1 and induces apoptosis . Canfosfamide also inhibits the catalytic kinase activity of DNA-dependent protein kinase ( DNA-PK ). Canfosfamide produces an anticancer alkylating agent and a glutathione derivative after activation. Canfosfamide can be used to research malignancies.

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA-PK | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-16124
• CAS No.: 158382-37-7
• Molecular Formula: C26H40Cl4N5O10PS
• Molecular Weight: 787.47
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source