MAO-B-IN-30 (compound IS7) is a potent, selective and cross the blood-brain barrier MAO-B inhibitor with IC 50 values of 19.176, 0.082 µM for MAO-A and MAO-B , respectively. MAO-B-IN-30 shows antiproliferative activity and non-cytotoxic. MAO-B-IN-30 reduces TNF-alpha , IL-6 , NF-kB levels. MAO-B-IN-30 has the potential for the research of Parkinson's disease.
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