P-gp inhibitor 20

Overview

P-gp inhibitor 20 (compound H27) is a low cytotoxicity P -glycoprotein ( P -gp ) inhibitor. P-gp inhibitor 20 inhibits the efflux function of P -gp in a dose-dependent manner (without affecting the expression of P -gp), thereby reversing the multidrug resistance (MDR) of MCF-7/ADR cells, with an IC 50 value of 46.6 nM. P-gp inhibitor 20 can be used for cancer research.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > P-glycoprotein

Product Information

• Catalog No.: HY-161260
• CAS No.: 3040917-33-4
• Molecular Formula: C30H28N4O3Se
• Molecular Weight: 571.53
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source