PARP1/c-Met-IN-1

Overview

PARP1/c-Met-IN-1 (Compound 16) is a selective dual inhibitor for PARP1 and c-Met , with IC 50 s of 3.3 and 32.2 nM, respectively. PARP1/c-Met-IN-1 induces cell apoptosis and cell cycle arrest in G2/M phase in MDA-MB-231 cells. PARP1/c-Met-IN-1 exhibits antitumor activity in mice.

Application

Products | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > PARP | Products > Signaling Pathways > c-Met/HGFR | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-161372
• CAS No.: 2944101-99-7
• Molecular Formula: C40H33FN8O4
• Molecular Weight: 708.74
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source