Linsidomine hydrochloride

Overview

Linsidomine hydrochloride (SIN-1 chloride) is a spontaneous ROS/RNS generator and peroxynitrite donor. Linsidomine hydrochloride is a vasodilator and platelet aggregation inhibitor. Linsidomine hydrochloride induces oxidative stress-induced chondrocyte apoptosis and necrosis . Linsidomine hydrochloride inhibits the migration, proliferation and neointima formation of vascular smooth muscle cells by inhibiting the expression of annexin A2 . In addition, low doses of Linsidomine hydrochloride shows protective effects on Zn 2+ treated nerve cells.

Application

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Product Information

• Catalog No.: HY-101200
• CAS No.: 16142-27-1
• Molecular Formula: C6H11ClN4O2
• Molecular Weight: 206.63
• Purity: 99.97%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Solubility: ≥ 2.5 mg/mL (12.10 mM); Clear solution
• Availability: In-stock

Source

Original product source