HDAC-IN-73

Overview

HDAC-IN-73 (compound P-503) is a histone deacetylase ( HDAC ) inhibitor. HDAC-IN-73 shows IC 50 s values of 0.17, 0.49 µM for HDAC1 and HDAC6 , respectively. Notably, HDAC-IN-73's inhibitory potency against HDAC6 is heightened, exhibiting a 9-fold greater efficacy than PsA ( HY-N2150 ) ( IC 50 =3.9 μM). HDAC-IN-73 shows potent antiproliferative activity, induces apoptosis , and causes cell cycle arrest at G2 / M phase. HDAC-IN-73 has the potential to be used for the research of cancer such as colon cancer .

Application

Products | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > HDAC

Product Information

• Catalog No.: HY-161688
• CAS No.: 2323571-16-8
• Molecular Formula: C22H24Br2N4O6Se2
• Molecular Weight: 758.18
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source