TX-2552

Overview

TX-2552 is an orally active tyrosine DNA phosphodiesterase 1 ( TDP1 ) inhibitor with an IC 50 value of 0.62 μM. TX-2552 can enhance the clastogenic activity of Topotecan ( HY-13768 ) in mouse bone marrow cells, as well as the anti-tumor effect of Topotecan ( HY-13768 ) in Krebs-2 ascites tumor mice.

Application

Products | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Others | Products > Signaling Pathways > Phosphodiesterase (PDE)

Product Information

• Catalog No.: HY-161853
• CAS No.: 2446767-14-0
• Molecular Formula: C25H25FO3
• Molecular Weight: 392.46
• Purity: 99.69%
• Storage: Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Availability: In-stock

Source

Original product source