GPX4 activator 1

Overview

GPX4 activator 1 (Compound A9) is a allosteric activator of GPX4 ( K d = 5.86 μM, EC 50 = 19.19 μM). GPX4 activator 1 can selectively act on ferroptosis and prevent the accumulation of intracellular lipid peroxides caused by ferroptosis inducers.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Glutathione Peroxidase | Products > Signaling Pathways > Ferroptosis

Product Information

• Catalog No.: HY-161928
• CAS No.: 1030098-18-0
• Molecular Formula: C20H26N6O2S
• Molecular Weight: 414.52
• Purity: 99.02%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (12.06 mM); Clear solution
• Availability: In-stock

Source

Original product source