RIPK1-IN-20

Overview

RIPK1-IN-20 (compound 13c) has a favorable RIPK1 kinase inhibition activity with an IC 50 value of 59.8 nM. RIPK1-IN-20 blocks TNFα-induced necroptosis in both human and murine cells ( EC 50 =1.06–4.58 nM).

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > RIP kinase | Products > Signaling Pathways > Necroptosis

Product Information

• Catalog No.: HY-162097
• CAS No.: 3026543-19-8
• Molecular Formula: C28H26F3N5O4
• Molecular Weight: 553.53
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source