GGTI-2154 is a potent and selective inhibitor of geranylgeranyltransferase I ( GGTase I) , with an IC 50 of 21 nM. GGTI-2154 shows more than 200-fold selectivity for GGTase I over FTase (IC50=5600 nM). GGTI-2154 can be used for the research of cancer .
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