GGTI-2418

Overview

GGTI-2418 is a highly potent, competitive, and selective geranylgeranyltransferase I ( GGTase I ) inhibitor. GGTI-2418 inhibits GGTase I and FTase activities with IC 50 s of 9.5 nM and 53 μM, respectively. GGTI-2418 also increases p27(Kip1) and induces significant regression of breast tumors.

Application

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Product Information

• Catalog No.: HY-16231
• CAS No.: 501010-06-6
• Molecular Formula: C23H31N5O4
• Molecular Weight: 441.52
• Purity: 99.89%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 2.08 mg/mL (4.71 mM); Clear solution
• Availability: In-stock

Source

Original product source