I-As-1 is a potent inhibitor of Bruton’s tyrosine kinase ( BTK ), with the IC 50 of 2.35 nM. I-As-1 shows antiproliferative activities among Ramos cells and OCI-LY10 cells with IC 50 s of 0.52 μM and 0.11 μM, respectively.
Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > Btk
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