PTPN2/1-IN-3

Overview

PTPN2/1-IN-3 (compound 4) is a modified, orally active PTPN2/N1 inhibitor based on ABBV-CLS-484 ( HY-145923 ). PTPN2/1-IN-3 has anti-tumor effects, inhibiting PTPN2 with an IC 50 of 9.3 nM and having an oral bioavailability of 93% in mice.

Application

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Product Information

• Catalog No.: HY-162428
• CAS No.: 3032920-59-2
• Molecular Formula: C14H18FN3O4S
• Molecular Weight: 343.37
• Purity: 99.89%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (7.28 mM); Clear solution
• Availability: In-stock

Source

Original product source