L-732138

Overview

L-732138 is a selective, potent and competitive neurokinin-1 (NK-1) receptor antagonist with an IC 50 of 2.3 nM. L-732138 has 200-fold more potent in cloned human NK-1 receptors than cloned rat NK-1 receptors , and has > 1000-fold more potent than human NK-2 and NK-3 receptors. L-732138 can reduce hyperalgesia and has antitumor action.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Cancer | Products > Disease Areas > Depression | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Neurological Disease | Products > Research Areas > Cancer | Products > Signaling Pathways > Neurokinin Receptor

Product Information

• Catalog No.: HY-101249
• CAS No.: 148451-96-1
• Molecular Formula: C22H18F6N2O3
• Molecular Weight: 472.38
• Purity: 99.9%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 2 years , -20°C, 1 year
• Solubility: ≥ 6.25 mg/mL (13.23 mM); Clear solution
• Availability: In-stock

Source

Original product source