BPR5K230

Overview

BPR5K230 is a dual inhibitor for the receptor tyrosine kinase MER and AXL , with IC 50 of 4.1 nM and 9.2 nM. BPR5K230 inhibits the proliferation of Ba/F3-MER with IC 50 of 5 nM. BPR5K230 exhibits good pharmacokinetic characteristics in mice, exhibits anti-inflammatory and antitumor against 4T1, MDA-MB-231, MC38 and Hepa1?6 in mouse models.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > TAM Receptor

Product Information

• Catalog No.: HY-162645
• CAS No.: 3029897-97-7
• Molecular Formula: C37H30FN7O4
• Molecular Weight: 655.68
• Purity: 99.82%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 0.2 mg/mL (0.31 mM); Clear solution
• Availability: In-stock

Source

Original product source