Kartogenin

Overview

Kartogenin (KGN) is an inducer of chondrogenic tissue formation ( EC 50 : 100 nM). Kartogenin induces chondrogenesis by binding to fibrin A, disrupting its interaction with the transcription factor core binding factor beta subunit (CBFβ), and by modulating the CBFβ-RUNX1 transcriptional program. Kartogenin also promotes tendon-bone junction (TBJ) wound healing by stimulating collagen synthesis. Kartogenin is widely used in cell-free therapy in the field of regeneration for cartilage regeneration and protection, tendon-bone healing, wound healing and limb development. Kartogenin promotes cartilage repair, coordinates limb development, and is also used in osteoarthritis (OA) research.

Application

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Product Information

• Catalog No.: HY-16268
• CAS No.: 4727-31-5
• Molecular Formula: C20H15NO3
• Molecular Weight: 317.34
• Purity: 99.05%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 2.5 mg/mL (7.88 mM); Clear solution
• Availability: In-stock

Source

Original product source