HDAC3-IN-5

Overview

HDAC3-IN-5 (9c) is a HDAC3 selective inhibitor, with IC 50 values of 4.2 nM, 1629 nM and 298.2 nM for HDAC3 , HDAC2 , HDAC1 , respectively. HDAC3-IN-5 (9c) can effectively induce apoptosis in MV4-11 cells in vitro and reduce the expression of anti-apoptotic proteins, the development of HDAC3 selective inhibitors may serve as a potential lead compound to reverse Venetoclax resistance.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > HDAC | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-162769
• CAS No.: 3095232-95-1
• Molecular Formula: C28H38N4O
• Molecular Weight: 446.63
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source