Lck-IN-2 (compound 12a) is an inhibitor of Lymphocyte-specific protein tyrosine kinase ( Lck ) with IC 50 of 10.6 nM. Lck-IN-2 reveals efficacy in colon cancer cells with GI 50 s of 0.24-1.26 μM. Lck-IN-2 exhibits an apoptotic effect in Colo201 cells.
Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Src | Products > Signaling Pathways > Apoptosis
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