EZH2/HSP90-IN-29

Overview

EZH2/HSP90-IN-29 is a dual inhibitor for EZH2 and HSP90 , with IC 50 s of 6.29 nM and 60.1 nM, for EZH2 and HSP90 , respectively. EZH2/HSP90-IN-29 increases apoptosis /necrosis-related gene expression, induces cell cycle arrest at M phase and inhibits reactive oxygen species (ROS) catabolism pathway. EZH2/HSP90-IN-29 is able to cross the blood-brain-barrier (BBB).

Application

Products | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Drug Resistance | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > Histone Methyltransferase | Products > Signaling Pathways > HSP | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-163288
• CAS No.: 3033571-35-3
• Molecular Formula: C40H48N4O6
• Molecular Weight: 680.83
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source