PD-1/PD-L1-IN-39 (X 14) is an orally active PD-1/PD-L1 inhibitor with a IC 50 value of 15.73 nM. PD-1/ PD-L1-in-39 has a good binding affinity for human and mouse PD-L1 , with K D values of 14.62 nM and 392 nM, respectively. PD-1/PD-L1-IN-39 has antitumor activity.
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