J-1149

Overview

J-1149 is a potent ALK5 inhibitor, with an IC 50 value of 0.017 μM. J-1149 also shows weak p38α MAP kinase inhibitory activity, with an IC 50 value of 0.435 μM. J-1149 can be used for liver fibrosis research.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Signaling Pathways > TGF-β Receptor | Products > Signaling Pathways > p38 MAPK

Product Information

• Catalog No.: HY-163429
• CAS No.: 2883580-95-6
• Molecular Formula: C25H24N8O
• Molecular Weight: 452.51
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source