WRN inhibitor 10

Overview

WRN inhibitor 10 (Compound P24) is an inhibitor for the Werner helicase WRN with an IC 50 of 1.1 nM. WRN inhibitor 10 inhibits the proliferation of cancer cell SW48 with IC 50 of 39 nM. WRN inhibitor 10 exhibits good liver microsomal stability and film permeability. WRN inhibitor 10 exhibits good pharmacokinetic characteristics in CD-1 mice.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-163797
• CAS No.: 3049092-06-7
• Molecular Formula: C31H29BrClN9O5S
• Molecular Weight: 755.04
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source