CM-444

Overview

CM-444 is inhibitor for HDAC ( IC 50 is 6 nM-0.6 μM) and DNA methyltransferases ( DNMT , IC 50 is 1.8-2.3 μM). CM-444 is an inducer for the differentiation of acute myeloid leukemia cells. CM-444 exhibits anti-leukemic activity and improves the survival rate in mouse models.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > HDAC | Products > Signaling Pathways > DNA Methyltransferase

Product Information

• Catalog No.: HY-163803
• CAS No.: 2256079-52-2
• Molecular Formula: C27H30N6O5
• Molecular Weight: 518.56
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source