CDD-1653

Overview

CDD-1653 is a potent and selective BMPR2 inhibitor ( IC 50 =2.8 nM). CDD-1653 reduces the ability of ATP to bind to the kinase domain of BMPR2 , thereby affecting the phosphorylation of SMAD1/5/8 transcription factors, which play a key role in the BMP signaling pathway. CDD-1653 can be used to study diseases related to the BMP signaling pathway.

Application

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Product Information

• Catalog No.: HY-164145
• CAS No.: 3034216-44-6
• Molecular Formula: C21H22N6O4S
• Molecular Weight: 454.50
• Purity: 99.38%
• Storage: Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
• Solubility: ≥ 5 mg/mL (11.00 mM); Clear solution
• Availability: In-stock

Source

Original product source