diABZI-V/C-Mal

Overview

diABZI-V/C-Mal is a STING agonist (with a STING EC 50 of 314 nM in TH1 dual reporter cells) and a Cathepsin B substrate. diABZI-V/C-Mal activates STING , thereby triggering the IRF3 signaling pathway. diABZI-V/C-Mal is cleaved by Cathepsin B to regenerate diABZI-NH 2 .

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > STING | Products > Signaling Pathways > Cathepsin

Product Information

• Catalog No.: HY-164278
• CAS No.: 3035557-55-9
• Molecular Formula: C67H83N19O14
• Molecular Weight: 1378.49
• Purity: 99.28%
• Storage: -20°C, sealed storage, away from moisture * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
• Availability: In-stock

Source

Original product source