SHP2-IN-31

Overview

SHP2-IN-31 is a SHP2 inhibitor, with IC 50 s of 13 nM (Wild-type SHP2 ), >10000 nM (SHP1), >10000 nM ( SHP2 E76K) . SHP2-IN-31 inhibits pERK in a panel of tumor cells. SHP2-IN-31 inhibits tumor growth in RTK/KRAS-driven xenograft models.

Application

Products | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Signaling Pathways > SHP2 | Products > Signaling Pathways > ERK

Product Information

• Catalog No.: HY-164427
• CAS No.: 2411321-35-0
• Molecular Formula: C21H26Cl2N4O2
• Molecular Weight: 437.36
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source