GTCpFE

Overview

GTCpFE inhibits IKKα/β in the NF-κB pathway with anti-inflammatory activities and blocks p65 nuclear entry, which consists of Dimethyl fumarate (DMF) ( HY-17363 ) linked to Aspirin (ASA) ( HY-14654 ). GTCpFE exhibits selective anti-cancer stem-like cell (CSC) activity by reducing mammosphere growth and the CD44 + CD24 - immunophenotype. GTCpFE inhibits breast cancer stem cells , an important NFκB- and PGE2-dependent phenotype in aggressive cancers.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > NF-κB | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > IKK | Products > Signaling Pathways > NF-κB

Product Information

• Catalog No.: HY-164480
• CAS No.: 1588866-45-8
• Molecular Formula: C22H20O8
• Molecular Weight: 412.39
• Purity: 99.98%
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source